For me, it's the heart of the album. Guy's voice aches with pain and passion; it all comes to a head with the line "Send up a prayer in my name". You just don't get such a perfect marriage of words in music in modern music any more, which is why - for me - Elbow stand head and shoulders above the rest.
The poetry and symbolism in the lyrics is bloody outstanding. And then you have such evocative playing from the rest of the band. I never cease to be moved by this song; it's the song that I play to people who've never heard of Elbow before (there's not many about these days!) to show them what all the fuss is about.
The story about Guy's sister wanting to get out of the TV industry is interesting. I'd always assumed it was about the character of the song, up there with his TV in his lonely tower crane, needing to get his head out of the TV and interact with the real world.